| Thu, Dec 29 2011 | Indianapolis Colts (2-13) and Jacksonville Jaguars (4-11) Close Out Regular Season |
| Thu, Dec 22 2011 | Indianapolis Colts (1-13) Face Off Against Houston Texans (10-4) |
| Thu, Dec 15 2011 | Indianapolis Colts (0-13) Face Tennessee Titans (7-6) |
| Thu, Dec 08 2011 | Indianapolis Colts (0-12) Seek to Upend Baltimore Ravens (9-3) |
| Thu, Dec 01 2011 | Indianapolis Colts (0-11) Face Tough Task Against New England Patriots (8-3) |
| Thu, Nov 24 2011 | Indianapolis Colts (0-10) Face Carolina Panthers (2-8) |
| Thu, Nov 10 2011 | Indianapolis Colts (0-9) Square Off Against Jacksonville Jaguars (2-6) |
| Thu, Nov 03 2011 | Indianapolis Colts (0-8) Face Atlanta Falcons (4-3) |
| Fri, Oct 28 2011 | Indianapolis Colts (0-7) Look to Upset Tennessee Titans (3-3) |
| Sun, Oct 23 2011 | Indianapolis Colts (0-6) Try to Derail New Orleans Saints (4-2) |
| Sun, Oct 16 2011 | Indianapolis Colts (0-5) Face Cincinnati Bengals (3-2) |
| Sun, Oct 09 2011 | Indianapolis Colts (0-4) Face Kansas City Chiefs (1-3) |
| Mon, Oct 03 2011 | Indianapolis Colts (0-3) Try to Derail Tampa Bay Buccaneers (2-1) |
| Sun, Sep 25 2011 | Indianapolis Colts (0-2) Face Tough Task Against Pittsburgh Steelers (1-1) |
| Sun, Sep 18 2011 | Indianapolis Colts (0-1) Battle Cleveland Browns (0-1) |
| Sun, Sep 11 2011 | Indianapolis Colts Kick Off Season Versus Houston Texans |
| Sun, Jan 02 2011 | Indianapolis Colts (9-6) Finish Regular Season Versus Tennessee Titans (6-9) |
| Sun, Dec 26 2010 | Indianapolis Colts (8-6) Take On Oakland Raiders (7-7) |
| Sun, Dec 19 2010 | Indianapolis Colts (7-6) Clash with Jacksonville Jaguars (8-5) |
| Thu, Dec 09 2010 | Indianapolis Colts (6-6) Go Up Against Tennessee Titans (5-7) |
| Sun, Dec 05 2010 | Indianapolis Colts (6-5) Take On Dallas Cowboys (3-8) |
| Sun, Nov 28 2010 | Indianapolis Colts (6-4) Face San Diego Chargers (5-5) |
| Sun, Nov 21 2010 | Indianapolis Colts (6-3) Square Off Against New England Patriots (7-2) |
| Sun, Nov 14 2010 | Indianapolis Colts (5-3) Take On Underdog Cincinnati Bengals (2-6) |
| Sun, Nov 07 2010 | Indianapolis Colts (5-2) Face Philadelphia Eagles (4-3) |
| Mon, Nov 01 2010 | Indianapolis Colts (4-2) Face Houston Texans (4-2) |
| Sun, Oct 17 2010 | Indianapolis Colts (3-2) Take On Washington Redskins (3-2) |
| Sun, Oct 10 2010 | Indianapolis Colts (2-2) Should Control Kansas City Chiefs (3-0) |
| Sun, Oct 03 2010 | Indianapolis Colts (2-1) Heavily Favored Against Jacksonville Jaguars (1-2) |
| Sun, Sep 26 2010 | Indianapolis Colts (1-1) Take On Denver Broncos (1-1) |
